Bone grafts are commonly required to treat defects in the skeletal system caused by injury, disease or other defects. Defects often require such grafts to maintain space and provide a matrix for healing. The properties of the graft must support the healing response that is due to various mechanisms of bone healing known as osteoconduction, osteoinduction and osteogenesis. Osteoconduction is the ability of the graft to act as a matrix to support bone formation imitated by bone forming cells. Osteoinduction is a result of bone growth factors that stimulate differentiation of local cells to become bone forming cells, i.e. osteoblasts. Bone morphogenic proteins (BMP's) that are naturally occurring in bone, or that may be produced by recombinant gene technologies are responsible for osteoinduction. Osteogenesis refers to the ability of cells to directly form bone at the site of implantation due to normal physiological processes. These cells may be either resident at the graft site or transplanted to the site by autogenous bone, bone marrow aspirate, and/or implanted cells. There is a need for bone grafts to have osteoconductive, osteogenic and osteoinductive properties to support bone formation and healing.